Vibrio cholerae research @ Hammer Lab

The Hammer Lab at Georgia Tech studies how bacteria sense and respond to their environment. Recently we started investigating Type VI secretion systems and how V. cholerae use T6SS to invade and maintain their niche in both the environment and in human hosts.

Type VI secretion systems

Bacterial warfare using T6SS

T6SS acts like a hypodermic needle, delivering toxins across the membrane into a neighboring cell. 

Watch us work hosts our public and private projects, including their data and code. 

Visit our Git repositories

T6SS Predictor

Predict T6SS genes and loci in your strains of interest
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Predict your T6SS genes

  1. Bernardy EE, Turnsek MA, Wilson SK, Tarr CL, Hammer BK.2016. Diversity of Clinical and Environmental Isolates of Vibrio cholerae in Natural Transformation and Contact-Dependent Bacterial Killing Indicative of Type VI Secretion System Activity. Appl Environ Microbiol 82(9):2833-2842.
  2. Watve S, Thomas J & Hammer BK. 2015. Watve SS, Thomas J, Hammer BK.2015. CytR Is a Global Positive Regulator of Competence, Type VI Secretion, and Chitinases in Vibrio cholerae. PLoS ONE 10(9):e0138834.
  3. Antonova ES, Hammer BK. 2015 Genetics of Natural Competence in Vibrio cholerae and other Vibrios. Microbiol Spectrum 3(3):VE-0010-2014